Cryptorchidism means, "hidden testes" (crypt = hidden, orchid = testes). Also, some blood malignancies, including leukemia and non-Hodgkin lymphoma, have been described in patients with Poland syndrome. Undescended testes or cryptorchidism describes the incomplete descent of one or both testes from the abdomen through the inguinal canal, with a resultant absence from the scrotum. Poland syndrome has been associated with other syndromes, including Moebius syndrome (congenital bilateral facial paralysis with inability to abduct the eyes) and Klippel-Feil syndrome. AndroGel ® (testosterone gel) 1% and 1.62% CIII are indicated for replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone:. -Primary hypogonadism (congenital or acquired): Testicular failure due to conditions such as cryptorchidism, bilateral torsion, orchitis, vanishing testis syndrome, orchiectomy, Klinefelter Syndrome, chemotherapy, or toxic damage from alcohol or heavy metals. This means that having a mutation in only one of the 2 copies of the responsible gene (the NSD1 gene) is enough to cause signs and symptoms of the condition. About 80% of all undescended testes … It may be bilateral in up to 30% of cases. 95% of people with Sotos syndrome do not inherit the condition from a parent. In these cases, the condition is the result of a new (de novo) mutation that occurred for the … Sotos syndrome is inherited in an autosomal dominant manner. Testicular cancers are the most common neoplasm in men between the ages of 20 and 34 years. Epidemiology Testicular cancer is uncommon, accounting for less than 1% of all internal organ malignancies 2. Generally, unilateral cryptorchids are usually fertile, while bilateral cryptorchids are generally sterile. The suspected cause is that the spermatic cords, which attach each testicle to the body, fail to grow at the same rate as the rest of the child. The comparatively short spermatic cords gradually pull the testicles out of the scrotum and into the groin. This term describes the condition in which one (unilateral) or both (bilateral) testicles do not descend normally into the scrotum. This condition is known as acquired undescended testicles, or acquired cryptorchidism.
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